Wednesday, July 31, 2013

Planetary 'runaway greenhouse' more easily triggered, research shows

[unable to retrieve full-text content]It might be easier than previously thought for a planet to overheat into the scorchingly uninhabitable "runaway greenhouse" stage, according to new research.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/JJ6D3sb-6So/130730163146.htm

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Happy Birthday, Arnold Schwarzenegger! What Are His Top 10 Roles?

Source: http://www.thehollywoodgossip.com/2013/07/happy-birthday-arnold-schwarzenegger-what-are-his-top-10-roles/

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Former Dixon coach appears in Yolo County court

A 37-year-old Dixon man accused of having a sexual relationship with a 17-year-old girl -- and then threatening to hurt her if she told authorities about it -- made an appearance in Yolo Superior Court on Monday morning.

Davis police arrested Troy Anthony Hensley on May 30, following an alleged 3 1/2-month sexual relationship between him and the young Dixon resident in 2012. The alleged relationship took place at several Davis locations, and police from that city notified Dixon police about it before arresting Hensley during a traffic stop on Highway 113.

Hensley was a youth sports coach in Dixon, including work as a temporary football and basketball coach for the Dixon Unified School District. Police did not state whether he met the alleged victim while coaching.

In a statement, Davis police Lt. Glenn Glasgow said that "it was also determined that Hensley had made threats to harm the victim and others if she reported their relationship to the police."

He is charged with more than two dozen felonies, including unlawful sex with a minor and making criminal threats. Bail was originally set at $1 million but later lowered to $450,000, according to reports.

On Monday, Hensley appeared for a pre-trial hearing with his lawyer to ask for a continuance, according to reports. The request was granted by Judge David Rosenberg, with a new date set for Aug. 26.

Police also indicated that there may be other victims. The case remains under investigation.

Source: http://www.thereporter.com/news/ci_23758114/former-dixon-coach-appears-yolo-county-court?source=rss

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Tuesday, July 30, 2013

Newark Mayor Cory Booker not visiting Iowa

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Source: http://www.app.com/article/20130729/NJNEWS10/307290102/1007/NEWS03&source=rss

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Muslim Converts In Mexico Make Up A Diverse, Fast-Growing Community http://latin...

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Source: http://www.facebook.com/CAIRNational/posts/10151593556962695

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Japan protests Korean banner

Japan said Monday it has protested at the display of a banner criticising Tokyo when its football team played South Korea in the final match of the East Asian Cup in Seoul.

Chief Cabinet Secretary Yoshihide Suga told a news conference the display was "extremely regrettable", according to Kyodo News.

The Japanese government "will respond appropriately based on FIFA rules when the facts are revealed", Suga said, referring to the sport's governing body.

The Japan Football Association has submitted a letter of protest to the East Asian Football Federation (EAFF), public broadcaster NHK and other news reports said.

Japan won the cup Sunday after its men's team defeated South Korea 2-1.

During the match at the Olympic Stadium, South Korean fans displayed a giant banner reading, "There is no future for people who have forgotten their past" -- a reference to Japan's reluctance to acknowledge its colonial and militaristic history, including in Korea.

The banner, which may violate EAFF regulations banning political campaigns during its games, was taken down after the first half.

"It was regrettable," Japan Football Association president Kuniya Daini said, according to Kyodo. "We want the East Asian (Football) Federation to investigate and deal with the case firmly."

Japanese fans at the game waved the Rising Sun flag of their country's military -- seen as a symbol of its imperialistic past -- before they were asked to put it away.

Relations between the two countries are often prickly, with disputes often related to Japan's harsh 1910-45 rule over Korea. The acrimony sometimes clouds sporting fixtures.

A similar incident occurred when the two football teams met during the London Olympics last year. South Korea's Park Jong-Woo was banned for two games by FIFA and fined after he displayed a sign referring to a territorial dispute between the two countries.

Source: http://wwos.ninemsn.com.au/article.aspx?id=8697760

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Monday, July 29, 2013

'The Wolverine' claws way to top of box office

This publicity photo released by Twentieth Century Fox shows Hugh Jackman as Logan/Wolverine in a scene from the film, "The Wolverine." (AP Photo/Twentieth Century Fox, Ben Rothstein)

This publicity photo released by Twentieth Century Fox shows Hugh Jackman as Logan/Wolverine in a scene from the film, "The Wolverine." (AP Photo/Twentieth Century Fox, Ben Rothstein)

This publicity image released by 20th Century Fox shows Hugh Jackman in a scene from "The Wolverine." (AP Photo/20th Century Fox, Ben Rothstein)

(AP) ? "The Wolverine" slashed monsters and minions to debut atop the weekend box office.

The Fox film featuring Hugh Jackman's sixth turn as the claw-wielding superhero opened with $55 million in North America, according to studio estimates Sunday.

Last weekend's top movie, Warner Bros.' low-budget horror "The Conjuring," slipped to second place, adding another $22.1 million to its take, while "Despicable Me 2" was in third with $16 million. The Universal animated sequel, with its cast of cute, yellow minions, has made more than $600 million worldwide since it came out four weeks ago.

"The Wolverine," which is set in Japan and features an international cast, earned another $86.1 million overseas. The film's opening-week take surpassed the $120 million it cost to make, said Chris Aronson, Fox's head of domestic distribution.

"It's a huge opening for the clawed one," he said. "It played equally well from Maine to Maui."

Another Fox film, the animated snail-racing tale "Turbo," was in fourth place with $13.3 million. Adam Sandler's "Grown Ups 2" followed with $11.5 million.

Woody Allen's latest, "Blue Jasmine," enjoyed a stellar opening of its own, though on a much smaller scale. Starring Cate Blanchett, the film opened in just six theaters but still collected $612,767.

"It's one of the biggest opening per-theater averages ever for a non-animated film," said Paul Dergarabedian of box-office tracker Hollywood.com.

Ticket sales this weekend were up almost 30 percent over the same weekend last summer, he said.

"It was a good weekend to be a moviegoer because the choices just got a lot more interesting," Dergarabedian said, noting a mix that includes animated, independent and big-budget action offerings.

"Fruitvale Station," the Sundance winner already generating Oscar buzz, opened across the country and edged its way into the top 10, contributing to a summer box office that is up more than 10 percent over last year.

___

Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com. Where available, latest international numbers are also included. Final domestic figures will be released on Monday.

1. "The Wolverine," $55 million ($86.1 international).

2. "The Conjuring," $22.1 million.

3. "Despicable Me 2," $16 million.

4. "Turbo," $13.3 million.

5. "Grown Ups 2," $11.5 million.

6. "Red 2," $9.4 million.

7. "Pacific Rim," $7.5 million.

8. "The Heat," $6.85 million.

9. "R.I.P.D.," $5.85 million.

10. "Fruitvale Station," $4.65 million.

___

Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-07-28-US-Box-Office/id-e9594c53a7c445f7a03779ea84dd3b75

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Campaign against illegal immigrants strains coalition

By Andrew Osborn

LONDON (Reuters) - An advertising campaign designed to get illegal immigrants to leave Britain opened up a rift in the government on Monday when Prime Minister David Cameron's spokesman said it was working but his coalition partner said the idea was "offensive".

The trial campaign saw two vans drive around six London boroughs in the last week displaying billboards telling illegal immigrants to "Go Home or Face Arrest", part of a wider government crackdown aimed at reducing net migration - the numerical difference between people coming in and out of the country.

Urging people to contact the authorities "for free advice, and help with travel documents", the posters carried a big picture of a pair of handcuffs and reported how many illegal immigrants had been arrested in the last week.

Voluntary immigrant returns were the "most cost-effective" way of reducing illegal migration, officials said.

Immigration is a hot button issue in Britain, where Cameron is trying to stop an exodus of voters from his ruling Conservatives to a populist anti-immigration party before a parliamentary election in two years' time.

Conservative strategists believe the campaign will be popular with many voters, but the topic is an uncomfortable one for Cameron's junior coalition partner, the left-leaning Lib Dems.

Keen to distance themselves from the Conservatives in voters' minds before the next election, they have abandoned ideas for an amnesty for illegal immigrants and now advocate a tougher approach.

But they have bridled at the ad campaign.

'STUPID AND OFFENSIVE'

Business Secretary Vince Cable, a Lib Dem, called it "stupid and offensive", saying he thought it very unlikely to be continued.

"It is designed, apparently, to sort of create a sense of fear in the British population that we have a vast problem of illegal immigration. We have a problem, but it's not a vast one," Cable told the BBC's Andrew Marr Show on Sunday.

He said the Lib Dems had not been consulted about the initiative.

But a spokesman for Cameron, who is on holiday in Portugal, said on Monday that the prime minister didn't agree with Cable's criticism. "No is the short answer," the spokesman told reporters when asked whether he agreed the campaign was "stupid and offensive".

"The pilot is already working. The pilot is about targeting people who are here illegally and giving them the opportunity to leave the country voluntarily rather than be arrested, detained and removed."

The government would review the pilot's success and examine how and whether the campaign could be continued, he added, saying there had been "a great deal of interest" from illegal immigrants in the scheme.

Cameron has ruled with the Lib Dems since 2010, but the two have taken increasingly different positions on issues such as Britain's role in Europe and on reform of Britain's unelected upper house of parliament.

Many traditional supporters of the Lib Dems felt alienated when they struck a coalition deal with the Conservatives, a centre-right party, and have been further disenchanted by what they see as the coalition's "lurch to the right" on immigration and welfare policy.

(Editing by Raissa Kasolowsky)

Source: http://news.yahoo.com/immigration-numbers-pose-political-problem-cameron-023824742.html

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Group accuses Apple supplier of labor abuses

(AP) ? A labor rights group Monday accused a Chinese company that makes iPhones for Apple Inc. of abuses including withholding employees' pay and excessive working hours.

China Labor Watch said it found violations of the law and of Apple's pledges about working conditions at factories operated by Pegatron Corp., a Taiwanese company.

Conditions in Chinese factories that produce iPhones and other popular Apple products have been under scrutiny following complaints about labor and environmental violations by a different supplier, Taiwan's Foxconn, a unit of Hon Hai Precision Industry Co.

Apple said in a statement it was "committed to providing safe and fair working conditions" and would investigate the claims about Pegatron. The Taiwanese company's chief executive, in a separate statement, also promised to investigate.

China Labor Watch said its investigation covered two factories in Shanghai and one in Suzhou, a nearby city, that employ a total of 70,000 people. It found violations including discrimination against ethnic minorities and women, excessive work hours, poor living conditions, health and safety problems and pollution.

Pegatron assembles products including the iPhone 4, iPhone 4s and iPhone 5 for Apple, according to the report.

Apple said it confirmed one accusation by China Labor Watch ? that identity cards of some workers were being held by management ? and told Pegatron to stop.

Apple has published a code of conduct for its suppliers and joined the Fair Labor Association, a worker rights monitoring group. The association inspected Foxconn factories early last year and said in August that improvements it recommended were being carried out ahead of schedule.

Conditions in factories in China are a sensitive issue for foreign companies that outsource production of shoes, consumer electronics and other goods to local contractors.

In its report Monday, China Labor Watch said the majority of Pegatron production employees worked 66 to 69 hours a week, far above China's legal limit of 49 hours. It said pregnant women sometimes were required to work 11-hour days, more than the eight-hour legal limit, and employees were pressured to falsify time cards to conceal the violations.

The group accused Pegatron of "discriminatory hiring practices" including refusing to hire those older than 35 or members of China's Hui, Tibetan, or Uighur ethnic minorities.

The group said production line workers sometimes dump water laced with hazardous chemicals from cutting tools into sewers.

Apple, based in Cupertino, California, said it would send auditors to three Pegatron facilities this week to investigate the report's claims.

The company said it has conducted 15 comprehensive audits of Pegatron facilities since 2007, including surprise audits in the past 18 months. It said the audits covered more than 130,000 employees.

"Apple is committed to providing safe and fair working conditions throughout our supply chain," the company statement said. "If our audits find that workers have been underpaid or denied compensation for any time they've worked, we will require that Pegatron reimburse them in full."

The company said its own audit found Pegatron employees making Apple products worked 46 hours per week on average.

Pegatron, founded in 2008, also manufactures desktop and notebook personal computers, LCD televisions, broadband and wireless systems and other products.

"We take these allegations very seriously," said Pegatron CEO Jason Cheng in a statement. "We will investigate them fully and take immediate actions to correct any violations to Chinese labor laws and our own code of conduct."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-07-29-AS-China-Apple-Labor/id-1e8e19fc5fa74802a401f88d4ad85e62

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Sunday, July 28, 2013

Greenbo Opens New Scuba Refuge | LEX18.com | Lexington ...

GREENBO STATE RESORT PARK, Ky. (AP) - After year of planning and months of preparation, a 10-acre Scuba Refuge opened Saturday at Greenbo Lake State Resort Park.

Within minutes of the park's newest attraction opening, recreational scuba divers descended below the surface of the lake for the first time. The lake has long been used by local fire departments and industry for training exercises, but Saturday marked the first time recreational diving opened to the public.

Officials hope the refuge will help the park appeal to a new set of users and boost visitorship along with the local economy. Opened on a three-year trial basis, officials hope the attraction will someday become a permanent addition to the activities available to visitors.

Divers must register at the park's office and pay a daily fee of $12. The refuge, which averages 25-feet in depth, is open from 10 a.m. to 6 p.m. April through October.

Safety guidelines have been established and buoys warn boat traffic away from the area while divers are in the water. Divers must be open-water certified or higher to use the area, or must be accompanied by an instructor with the appropriate certification. The area is open to anglers and boaters when divers are not in the water, as signified by buoys and red and white "diver down" flags.

"I am so excited about this. It has been a long time coming," said Kentucky State Parks Commissioner Elaine Walker. Walker was joined by Ron Brooks, director of Kentucky Fish and Wildlife, Greenbo Manager Cary Lyle, Greenup County Judge-Executive Bobby Carpenter, State Representative Jill York R-Grayson, state Senator Robin Webb D-Grayson, Bobby Allen, executive director of Greenup County Tourism and president of Friends of Greenbo, and friends member Todd Eastham at the ribbon cutting ceremony.

"It was a community effort, we involved fish and wildlife. There were community meetings. There was compromise, and I think ultimately people are going to realize what a great thing this is for Greenbo State Resort Park, for our region and for our state," said Walker. "I think it's going to be great for the divers as well as the fisherman," she added. The refuge did face some opposition for many anglers.

"I think the big benefit of having a three year trial is that there is always fear about what you don't know. There is speculation about what is going to happen, so I think if you have three years' experience you can see what works, what may need to be adjusted a little bit," said Walker.

"I am hopeful this is going to become a full-time activity here at Greenbo Lake State Resort Park and that we can expand it to some of our other parks. We have people who are diving enthusiasts. We should be able to provide them a safe environment that is compatible with the other water sports and activities," she said.

Some of the first divers in the water on Saturday were Kyle Morgan, Scott Porter and Stephanie Flaugher, with the Grayson Volunteer Fire Department.

"It is good to see it finally opened up," said Morgan, who noted the trio had helped with previous clean ups in preparation for the refuge opening. "Today will just be for recreation," he said.

Morgan said the department's diving team has had to travel up to six hours in the past for training. "It's great to be able to have this here, 15 minutes from your backdoor," he said.

"It is great to have it close to home," agreed Porter, "I?think it's going to be a great asset to Greenbo lake and to the whole region and area."

"There are a lot of divers here in this area," added Flaugher, noting she has friends and neighbors who also travel long distances to dive.

To help entice divers to the park, Greenbo began offering special packages for accommodations. For $77 per person, Friday through Sunday, individuals receive a one-day Scuba pass, one night lodging, a continental breakfast and lunch. From Sunday through Thursday the same package costs $66.50 per person.

Source: http://www.lex18.com/news/greenbo-opens-new-scuba-refuge/

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Motorola Moto X camera app apk available for your Android phone

1. Shatter posted on 4 hours ago 0

How long till all the major features get put into custom roms making the software side of this phone pointless to anyone who can root their phone.

2. kozza3 posted on 4 hours ago 0

how could you say that, it wouldn't be pointless because you would get all of the features without voiding your warranty :P

3. AliNSiddiqui posted on 4 hours ago 3

The always on voice control and always on display can't be put on other phones without having a MAJOR MAJOR hit on battery life. Moto X has specific cores and display built in a specific way to save battery.

4. TheLolGuy posted on 3 hours ago 0

That's true. At least any phones with OLED screens should technically be able to get the cool notifications feature! I'm not sure if its worth doing on a Galaxy S4 though. Trading all the sensors functionality for that isn't worth it for my use case.

I don't even think the new camera functions would work well for anything other than the Moto X too. Without ClearPixel, maybe fast shutter speeds or some algorithms will funk with your camera and give you messed up pictures?

13. saiki4116 posted on 1 hour ago 0

I do remember that during S4 launch video, they have said that they have a co processor for sensors. the octa core X8 is just mere marketing. It all boils down how google is going to use that co processor to make a difference in real time usage. It's just like a solution for videos, where application cores delegate task to Hardware video encoders and decoders, which are essentially co processing units optimized for hardware implementation of the codec software.

5. c.sanchez posted on 3 hours ago 0

How do you install it please help?

9. proto posted on 2 hours ago 0

you have to enable unknown sources in your security settings and install it by some file explorer app (like ES file explorer... or "my files" app which have samsung with touchwiz pre-installed)

7. InspectorGadget80 posted on 3 hours ago 0

ONLY A FEW MORE days too go! now i have too decide on the X PHONE or the Z ULTRA

8. MingLiangChen posted on 2 hours ago 0

To 5. and 6. , please click on the source link right below the camera UI image.
"source: MotoXCameraAPK via RedmondPie"

10. HASHTAG posted on 2 hours ago 0

Downloaded it, and it's great!

12. HASHTAG posted on 1 hour ago 0

Well, I don't know anyone else's having this problem, but my camera won't flash when I have the settings on flash.

Source: http://www.phonearena.com/news/Motorola-Moto-X-camera-app-apk-available-for-your-Android-phone_id45781

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Theileria gets naked and rides the spindle

Hijacking of the cell by its uninvited invaders is one of the coolest things in biology. Not only do these parasites leech off its food, they also ride along with the cell machinery itself ? modifying parts of it for their own benefit, of course. Apicomplexans and microsporidia, obligate intracellular parasites during at least one stage of their life cycles, are among the masters of cytoterrorism* in the eukaryotic world.

*The NSA too should know about awesome parasites!

Apicomplexans live for cell invasion ? they?re even named after their apical complex, a highly specialised machine fine tuned for penetrating its victims. They sort of look like torpedoes:

Structure of a generalised apicomplexan in its invasion form. (Fowler et al. 2003 Adv Parasitol)

While wandering around a poster session at a conference last week, a particular poster reminded me of the existence of Theileria. Or, given how much thought I?ve given that bug, more like informed me about its existence. Theileria is a plague upon cattle in the tropical regions of Africa, and is an apicomplexan of the Piroplasmid affiliation. To orient ourselves in relation to the major apicomplexans studied, the agent of malaria, Plasmodium, is a Haemosporidian while felid-brain-ninja Toxoplasma is a a coccidian. Piroplasmids were traditionally considered a separate clade from them all, but are now found to be fairly close to Haemosporidians like Plasmodium (see 2011 tree in the apicomplexan ToLWeb page; tons of other good api? information there too).

Apicomplexans enjoy orgies in their primary host, which is usually an arthropod. The secondary host is merely a dispensable source of food, which is why parasites tend to be much crueler to the latter (eg. vertebrates like us, but sometimes plants too!). This is also why the two phases of the life cycle are rather different, given that their primary goals differ. Theileria?s main secondary host (primary = ticks) is the water buffalo, who act as a reservoir due to their better resistance. Cattle, on the other hand, are outsiders, and far less capable of dealing with the African parasite. Theileria does not mind feasting on non-buffalo from time to time, but curiously ? strains are found in to specialise in different (and more susceptible) non-buffalo, but tend to be all found in the buffalo reservoir. It?s like the strains usually hang out at the main party scene in the buffalo, but occasionally wander off on their own adventures. Sex, however, still happens in the tick.?For the students of parasitology, remember: primary host = orgy, secondary host = food.

You?re perfectly welcome to investigate Theileria?s life cycle (figure), but I don?t recommend it. Too many words and cell types.

This is the more or less ?typical? invasion strategy of apicomplexans, such Toxoplasma. In short, the parasite recognises a suitable cell surface to invade (through receptors and such), attaches itself, and begins to dig into the cell with its apical complex. As it invaginates the membrane inward, there is something akin to a sieve between the apical end of the parasite and the cell membrane, which removes the surface receptors of the host cell ? to avoid detection once inside. The apicomplexan glides through this sieve(=moving junction) and eventually the surrounding membrane buds off, leaving the parasite in its comfy customised vacuole inside the host. Then, as all parasites (and life in general), it feeds and breeds. Just to mess with us, Plasmodium ? which you?d think is ?typical? due to its importance to us (scientific logic!) ? and, yes, Theileria, have decided to do away with their conoids. The invasion process remains similar enough, luckily.

The invasion process of Toxoplasma. It?s sneaky. (Carruthers & Boothroyd 2007 Curr Op Microbiol)

In the case of our more familiar apicomplexans, the parasite remains in its parasitophorous vacuole, until it blows up the host and escapes. Theileria, on the other hand, likes to get more intimate with its host ? sometime after a successful invasion, it sheds the parasitophorous vacuole altogether by dissolving its membrane. (Shaw 2003 Tr Parasitol) At this point, it immediately begins constructing a mitotic spindle out of tubulin (provided by the host cell, of course!) Toxoplasma, in contrast, divides while still inside its vacuole, only abandoning it after blowing up the host cell. This is improved further by Theileria dividing synchronously with the host cell, for months before the breakout occurs. The parasite goes in direct contact with the host cytoplasm and harnesses its subsequent generations for slavery, from within. Again, be glad you?re not a cell ? although, there?s a cornucopia of parasites who do this sort of thing with multicellulars ? eg. Cordyceps fungus, or the neuro-hijacking barnacle of crabs, Sacculina, who castrates the female crab and takes advantage of its parenting.

Theileria invasion cycle, until the beginning of division. Note the parasitophorous vacuole dissolving, and the yellow spindle tubes. (Shaw 2003 Tr Parasitol)

Back to Theileria. Since it lives synchronously with its host for a while, it would be preferable for it to segregate fairly evenly between the host daughter cells. The parasite spends its time there as a multinucleate plasmodium ? its own cycle still must be regulated as to not multiply its way out of the host cell and blow it up. This multinucleated parasite goo (mmm!) must then be split between the resultant pair of host cells. How they accomplish that was the focus of the study by von Schubert?et al. 2013?PLoS Biol.?Let?s get a glimpse of what this looks like, below. The blue stains the DNA, both of the host and parasite ? those of the latter quite a bit smaller. The green highlights the parasite?s cytoplasm, which you can follow through division. Finally, the red marks the microtubules, both cytoplasmic and those integrated in the spindle apparatus. Note how the spindle seems to be involved in not only segregating the host?s chromosomes, but the parasite as well. The parasite even participates in the equatorial plate that defines metaphase, along with the chromosomes!

Cell division sequence of Theileria and its host cell. Theileria is in green, DNA is blue, red is tubulin (of the host cell, predominantly). Click to actually see what?s going on. (Modified from von Schubert et al. 2013 PLoS Biol fig 1).

In the paper, they showed that its intimate interaction with the spindle is essential for Theileria to split itself properly between the host cells. Furthermore, some of the host cell?s own proteins localised to the parasite ? suggesting a physical interaction between the host mitotic machinery and the parasite?s own proteins (not too surprising for a parasite). Below is a ?fishing experiment? (sometimes a FISHing experiment, if hybridisation is involved, ahaha (reason behind most biology fish jokes)). They synchronised the cells by inhibiting one of the protein machines controlling the cell cycle progress, and then removing the drug to get the cells back into motion. Another drug was also added to prevent the host cell division furrow from happening. This allows to block cells just before cytokinesis and seeing what certain proteins are associated with.

Von Schubert?et al. found one of the host?s mitotic proteins the parasite hijacks, Polo-Like Kinase (PLK1). Plk-s are involved in starting mitosis and cytokinesis, from the beginning of chromosome condensation (prophase) to the division of the cell itself (has highschool or undergrad come to haunt you yet?). One of the ?master regulators?, so to speak (though not as mighty as CDKs and cyclins, the cell?s ?clock? proteins). PLK localises to Theileria?s cell membrane, suggesting a close interaction between PLK and the parasite?s own membrane proteins. Of course, as with everything in cell biology, this does not have to be direct ? what specifically PLK binds to (and what, in turn, that protein binds to? etc) remains to be determined. Nevertheless, this demonstrates a direct interaction between Theileria and the host cell division machinery. PLK is associated with the chromosomal centromeres, so in a way, it appears that Theileria can pretend to be just another set of chromosomes.

Localisation patterns of PLK and one of Theileria?s surface proteins just before (G2), at the beginning, and at towards the end of mitosis. DNA is in blue. Yellow shows colocalisation (presence in the same area) between green and red signal ? ie, PLK1 and Theileria?s SP1. Curiously, it?s absent from the parasite during prometaphase (middle), but then returns back to the surface. It doesn?t appear to be known why quite yet. (Modified from von Schubert et al. 2013 PLoS Biol fig 2).

Theileria not only exposes itself upon invading its slave, but directly binds to the mitotic spindle ?to segregate.?In a similar manner, Toxoplasma takes advantage of the host centriole, but has an extra membrane between itself and the host?s mitotic stuff, thus the binding is much more indirect. You gotta be naked to properly ride a spindle. The authors have a great summary below, and I?ve only scratched the surface of the cell biology work they?ve done on this wonderful organism. I recommend checking it out, at least for the pretty microscopy.

Schematic summarising the division process. (von Schubert et al. 2013 PLoS Biol fig 11)

Synchronisation with ? or detection of in general ? the host?s cell cycle is an important puzzle in the life of many parasites.?? Fun fact: the periodic flashes of fever that accompany malaria result from Plasmodium escaping their host blood cells all at once, to quickly burrow into their next victims (eg. Mideo et al. 2013 [paywalled]). This completely overwhelms the immune system! Basically, a deadlier variant of periodical cicadas. Just as with the cicadas, a tantalising question lingers ? just how do they figure out the timing? Despite the incredible variety of different infection and replication strategies of apicomplexans, shown below for no other purpose but microscopy porn, they all have some interaction with their victim, and must time their attacks accordingly. Personally, I find that absolutely amazing!

Recommending the paper for cell biol enthusiasts. (Striepen et al. 2007 PLoS Path [open access])

A ?convenient? feature of global warming is that tropical diseases are starting to migrate northward. For example, it seems that typically-tropical Trypanosoma cruzi, the cause of Chagas Disease (which leads to heart muscles becoming replaced by the parasite ? lovely!), is becoming more and more prevalent in the American South. This is great news ? for neglected tropical diseases research. Many of them are caused by protists, so hopefully interest in protists ? but more importantly, non-northern diseases that don?t affect the Western world as much ? will increase and attract funding. Besides, don?t forget that much of the American South and Southeast (including Washington DC), is traditionally home to malaria. We are not as inherently free of Plasmodium as we wish to think. Someday, it may well be that Theileria, Nagana, and African Sleeping Sickness are no longer ?just? an African problem. Maybe that, rather than basic humanity, will be enough to begin seriously investigating prevention and cure of those nasty afflictions.

Curing people of parasites, of course ? but also learning more about the many ways in which they are biologically awesome. Like the coat-less, spindle-hijacking Theileria.

Source: http://rss.sciam.com/~r/sciam/basic-science/~3/Cz6LkVLllac/post.cfm

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Saturday, July 27, 2013

Chris Christie-Rand Paul tiff on foreign policy reflects deep rift in GOP

In Congress, the divide between Team Christie and a more libertarian Team Paul was on display in the debate over the Amash amendment that sought to de-fund the NSA surveillance program.

By David Grant,?Staff Writer / July 26, 2013

Sen. Rand Paul, R-Ky. speaks with reporters in Louisville, Ky., on Monday.

Timothy D. Easley/AP/File

Enlarge

The foreign policy tussle between Chris Christie and Rand Paul, two likely 2016 Republican presidential contenders, marks the most public flaring of a long-simmering debate between the GOP?s long-time hawkish bent and the libertarian infusion the party has experienced in the last two election cycles.

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When push comes to shove, do Republicans weigh in on the side of national security and foreign intervention or of privacy and greater international detachment? And which path will help grow a political party that even some of its leaders fear faces deep demographic challenges?

Of course, both Senator Paul (R) of Kentucky and New Jersey Governor Christie would argue their path does all those things ? they just strongly disagree about how to proceed.

?This strain of libertarianism that?s going through parties right now and making big headlines I think is a very dangerous thought,? Christie said on a panel in Aspen, Colo. on Thursday, according to the New York Times.

Later, he continued: ?The next attack that comes, that kills thousands of Americans as a result, people are going to be looking back on the people having this intellectual debate and wondering whether they put ?? before abruptly ending his thought.

In a Facebook post, Paul, who most famously launched an hours-long filibuster over domestic US drone use and who has pushed to cut off foreign aid to many restive Middle East nations, rejoined that ?Chris Christie thinks freedom is dangerous. What's dangerous is a foreign policy that borrows from China to pay people who burn our flag in Egypt.?

Paul?s political Facebook page was less restrained, calling Christie ?Obama?s favorite Republican? and wondering if the governor approves of sending weapons to ?al Qaeda allies? in Syria.

While the tiff is a spot of positioning between two presidential contenders at either end of a particular policy debate, it?s also an argument that reverberates deep down into the Republican Party.

In Congress, there?s a stark divide between Team Christie and Team Paul.

Rep. Peter King (R) of New York, a former chairman of the Homeland Security Committee and a veteran foreign policy hawk, said he ?isn?t saying no? to a potential presidential run in part because ?when I see people like Rand Paul talking about drones killing people out to get a cup of coffee, I don't want that to be the face of the national Republican Party," he told The Hill.

But the reason Congressman King, a 20-year House veteran, has found himself back in the congressional majority is because of a surge of more Paul-minded reinforcements like Rep. Raul Labrador (R) of Idaho. And those folks want more Rand, not less.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/Ib5Dso3mbRw/Chris-Christie-Rand-Paul-tiff-on-foreign-policy-reflects-deep-rift-in-GOP

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CESC to delist from London Stock Exchange

PTI

Sanjiv Goenka, chairman, CESC

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' + '' + google_ads[i].visible_url + ''; } } document.write(s); return; } // -->

Kolkata, July 26:??

RP Sanjiv Goenka group flagship firm CESC today secured shareholders? approval for delisting securities from the London Stock Exchange (LSE) to cut costs.

Stating that he could not recall when the company was listed on the LSE long ago, CESC chairman Sanjiv Goenka said that only one per cent of the total issued equity shares of CESC were currently listed.

?But as the market of the company?s shares in UK has practically frozen and the dealings in shares in recent years have been very low, the company decided to delist to save costs,? he said.

Out of about 40,000 shareholders, those in the UK were only around 200.

The company secured shareholders? approval for delisting from LSE at the AGM.

The company?s shares were also listed on the CSE, BSE and NSE and the existing GDRs listed on EuroMTF of the Luxembourg Stock Exchange.

Shares of CESC closed today closed at Rs 325.30 apiece, down 2.39 per cent on the BSE.

Meanwhile, CESC?s retail subsidiary Spencer?s will add 2.85 lakh sq ft by this fiscal from present operational space of 9.8 lakh sq ft.

(This article was published on July 26, 2013)

Source: http://www.thehindubusinessline.com/companies/cesc-to-delist-from-london-stock-exchange/article4956150.ece

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Traditional forest management reduces fungal diversity

[unable to retrieve full-text content]In the beech groves of Navarre, biologists have analyzed the influence exerted by forestry management on the fungi populations that decompose wood.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/eZzlBG93ZxE/130726092358.htm

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Can interviewers legally ask if you're married or have kids?

Can interviewers legally ask if you're married or have kids?

Great discussions are par for the course here on Lifehacker. Each day, we highlight a discussion that is particularly helpful or insightful, along with other great discussions and reader questions you may have missed. Check out these discussions and add your own thoughts to make them even more wonderful!

Discussion of the Day

Other Great Discussions

Get Involved

Great Discussions Any Time

For great discussions any time, be sure check out our user-run blog, Hackerspace. And today being Friday, don't forget to check out this week's Open Thread.

If you've got a cool project, inspiration, or just something fun to share, send us a message at tips@lifehacker.com.

Happy Lifehacking, everybody!

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/2a4y-NJW91c/can-interviewers-legally-ask-if-youre-married-or-have-927305180

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Thursday, July 25, 2013

Bugshot updated with blur tool to hide all your privates

Bugshot, the fast, simple screenshot annotation and bug reporting tool by Marco Arment has been updated to version 1.1 and, in addition to fixes, now sports both a handy "Open in..." feature, as well as a blur tool for covering sensitive information. Or body parts. We don't judge. In regards to how the blur tool works, Arment had this to say on Twitter:

So it?s not just a straight pixelate ? it?s multiple lossy operations, with random parameter adjustments (with numbers from the secure RNG).

That was to try and make the tool more secure. It also means, according to Arment, that the tool will generate different blur patterns all the time, so if you don't like one, just nudge the area and it'll generate a new one, hopefully more in keeping with your pixel-prefs.

Scrolling is also improved on iOS 6, and the gallery now contains larger thumbnails so you can more easily pick just exactly the screenshot you want to work on. Arment has also made Bugshot even more iOS 7-like, with nicely rendered, symmetrical zoom animations to both open in, and cancel back out, screenshots.

If you've already bought Bugshot, the update is ready and waiting for you. If you haven't tried it yet, you can grab it right now from the App Store. When you try out the blur tool, let me know what you think.

    


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/iZO2UdirNGA/story01.htm

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Wednesday, July 24, 2013

State drops charges against Florida LB Morrison

By Chip Patterson | College Football Writer

The State Attorney's Office has dropped the misdemeanor charges against Florida linebacker Antonio Morrison for barking at a police dog and resisting arrest.

According to the Associated Press, State Attorney Bill Cervone said the "dismissal is based on the lack of evidence to warrant much less legally sustain those charges, and the complete inappropriateness of pursing court action against Morrison, or anyone else, under the circumstances involved."

Cervone told the AP that he reviewed the tape and did not see any resistance "beyond questioning the actions of law enforcement, which is not illegal."

The incident, which occurred Sunday morning, has been reviewed by authorities. Alachua County Sheriff Sadie Darnell told the Gainesville Sun on Monday that Morrison should have received a warning instead of being arrested.

The Gators' linebacker was walking in a group past a police vehicle when he began to bark at a police K9 in the car. That's when Morrison began to interact with an officer and was eventually arrested and charged with the two misdemeanors.

''I would expect that Morrison has learned that being out at that hour of the night under those circumstances is setting himself up for a situation where he could risk and lose a great deal,'' Cervone told the AP. ''However, counseling him about where he was and whatever he was doing is not the function of my office. I can only concern myself with criminal culpability, of which there is none.''

Florida kicks off the 2013 season against Toledo, then travels to Miami to face the preseason ACC Coastal Division favorite on Sept. 7. If there is a time when the Gators defense needs Morrison early, it will be against Hurricanes' running back Duke Johnson and the high-powered Miami offense.

"I'm extremely disappointed in Antonio Morrison's decision making," Gators' coach Will Muschamp said in an official statement after the arrest. "He has been suspended from the team and will miss at least two games to begin the season."

It is not known whether Muschamp will amend or reverse his decision.

Morrison's first arrest of the offseason came on June 16 on charges of simple battery. He later accepted a deferred prosecution agreement, which will reportedly not be affected if the dog barking charges are dropped. The Gainesville Sun also obtained a video of the incident with the K9 cop, you can check it out below.


Eye on College Football is maintained by the four handsomest men to ever handsome: Tom Fornelli, Jerry Hinnen, Chris Huston, and Chip Patterson. Follow Eye on College Football on Twitter, discover the meaning of life.

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'); handlers.failure(); } else{ removeLfError(); handlers.success(); } }; function updateAuthorLinks(){ $('.fyre-comment-username').each(function() { $(this).click(function() { window.location.href = $(this).attr('href'); }); }); $('.fyre-comment-author').each(function() { $(this).click(function() { window.location.href = $(this).attr('href'); }); }); } function updateOneLineComments(){ //console.log("Checking Comments"); $(".fyre-comment-wrapper").each(function() { if ($(this).find(".fyre-comment").css('display') != 'none'){ var commentText = $(this).find(".fyre-comment").html(); if (commentText != null){ var loopCtr = 0; // for IE8 while ( (commentText.indexOf("

",' '); loopCtr++; } //console.log(commentText); $(this).find(".fyre-comment").css('display','none'); $(this).find(".fyre-comment-head").append(commentText); } // end check for blank text } //console.log("Checking Height"); cntHeight = $(this).find(".fyre-comment-head").height(); if (cntHeight > 0){ //console.log("Setting Height"); cntHeight = -1 * ((cntHeight / 2) + 12); $(this).find(".fyre-flag-link").css('top',cntHeight); } }); } function change_profile_link(){ $(".fyre .fyre-box-list .fyre-edit-profile-link a").attr("href",'#'); $(".fyre .fyre-box-list .fyre-edit-profile-link a").attr("alt",''); $('.fyre .fyre-box-list .fyre-edit-profile-link a').click(function() { return false; }); $('.fyre .fyre-box-list .fyre-edit-profile-link').remove(); $(".fyre .fyre-comment-head .fyre-comment-username").attr("href",'#'); $(".fyre .fyre-comment-head .fyre-comment-username").attr("target",''); $(".fyre .fyre-comment-head .fyre-comment-username").attr("alt",''); $('.fyre .fyre-comment-head .fyre-comment-username').click(function() { return false; }); $('.fyre .fyre-comment-head').each(function() { var alltxt = $(this).html(); var nickname = $(this).find('.fyre-comment-username').html(); if (!(nickname == null)){ alltxt = "

Source: http://feedproxy.google.com/~r/cbssportsline/cfb_news/~3/aZ0hZmUsehs/attorney-florida-lb-antonio-morrisons-charges-to-be-dropped

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